Research Fellow on Imaging Neurodegeneration

Singapore Bioimaging Consortium
Singapore, Singapore
Expires: Open until filled
Posted: March 30, 2011
Neuroimaging
Post doc
  • Research Fellow on Imaging Neurodegeneration
    1.289436 103.84998
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Job Description

Several postdoc positions are available in the Magnetic Resonance Imaging Group, Singapore Bioimaging Consortium (SBIC) in Singapore. SBIC is a national research institute dedicating on advancing pre-clinical imaging and its translation to clinical applications. SBIC is composed of four major labs studying from animal models, imaging probe design, imaging techniques, to data processing. For further information about SBIC, please visit our website: http://www.sbic.a-star.edu.sg/.

The research focus of the group is on the development of MRI methods and imaging biomarkers for detection of neurodegeneration and regeneration in rodent models. One project is to study the structural and functional connectivity in models of axonal degeneration using techniques such as DTI, magnetization transfer, resting-state fMRI, etc. The other project is to develop functional imaging, including BOLD/CBV fMRI, perfusion, manganese enhanced MRI, CEST and PET, to understand how metabolic disorders such as diabetes exacerbate neurodegenerative diseases like dementia. We have very active interdisciplinary research teams consisting of people from engineering, physics, chemistry, biology, and neuroscience backgrounds. We also have extensive collaboration with major pharmaceutical companies to develop new methods for evaluating drug effects in the brain.

The successful candidate will have chance to work at the Clinical Imaging Research Center to translate the methods into clinical applications. The center currently hosts a Siemens 3T TIM Trio system and is expanding to include more imaging modalities and higher field MRI.

Facility and Equipment:

The lab currently hosts a Varian 9.4T MRI, a Bruker 7T ClinScan MRI, a Bruker 400MHz NMR, a NanoSPECT/CT, a Siemens microPET/CT, and a hyperpolarizer (Hypersense). Other facilities include a chemistry lab for imaging probe development, a molecular biology lab for developing transgenic animal models, and the SBIC-Nikon imaging center, which hosts all the advanced live cell optical imaging systems by Nikon. We also have access to animal behavior and radiochemistry facilities.

Qualifications:

We welcome highly-motivated people who want to explore new ideas and multidisciplinary researches to apply. Preferred background includes, but not limited to, neuroscience, physics, and engineering. Prior experience with in vivo MRI/NMR, programming language (C or Matlab), image processing and rodent imaging is preferred.

Contact Info:

Interested candidates should submit his/her CV to the following address: recruit@sbic.a-star.edu.sg

Contact

Kai-Hsiang Chuang, PhD
Email: chuang_kai_hsiang@sbic.a-star.edu.sg