News and Highlights
The INCF National Node of India, INNNI, report that their recent combined workshop and yearly meeting, held December 1-3, attracted nearly 150 participants. The workshop theme was "Hippocampus: From Synapses to Behavior".
In Neuroinformatics, researchers discussBrain Operation Database (BODB), an environment in which modelers and experimentalists can work together by making use of their shared empirical data, models and expertise.
Members of the INCF US Node discuss in Frontiers in Neuroinformatics how NEURON's Reaction-Diffusion (rxd) module in Python provides specification and simulation for genomics, proteomics, signaling cascades and reaction dynamics, coupled with the electrophysiological dynamics of the cell membrane.
In Frontiers in Neuroinformatics, members of the INCF German Node present Spike Viewer, an open source application designed to help researchers analyze data from electrophysiological recordings or neural simulations.
In this neuroscience special issue, Nature brings together reporting and expert opinion on efforts to apply current technologies and invent new ones to probe how the brain works. Thanks to such technologies researchers may be on the verge of opening new vistas in understanding just as long-term programmes in the European Union and United States could together pour more than US$2 billion into the study of the brain over the next decade.
In Frontiers in Computational Neuroscience, members of the INCF Dutch Node investigate the stability and sensitivity in a simple recurrent network of stochastic binary neurons and determine numerically the effects of correlation between the number of afferent (“in-degree”) and efferent (“out-degree”) connections in neurons.
In Frontiers in Neuroinformatics, researchers present the Northwestern University Schizophrenia Data and Software Tool (NUSDAST), an NIH-funded data sharing project that contains neuroimaging, cognitive, clinical, and genetic data.
The yearly application for the Erasmus Mundus doctoral training programme EuroSPIN ("European Study Programme in Neuroinformatics") is now open. This year's application deadline is December 15. Successful candidates will spend most of their time at two of the four partner universities (located in four different INCF Node countries), visit all other partner universities, and receive a joint PhD degree upon completion of their studies.
INCF is present at Neuroscience 2013 in San Diego, November 9 - 13 at the San Diego Convention Center. You are very welcome to come and visit us in booth #4128. As usual, we are hosting neuroinformatics demos in our booth during all the exhibition days. We also have a social, organized together with NIF, on Sunday November 10.
In Nature Neuroscience Reviews, members of the INCF Norwegian Node discuss how careful mathematical modelling and analysis are needed to take full advantage of the opportunities that LFP signals offer in understanding signal processing in cortical circuits and, ultimately, the neural basis of perception and cognition.
In Nature this week, by scanning blobs of brain activity, scientists may be able to decode people's thoughts, their dreams and even their intentions.
In Frontiers in Computational Neuroscience, members of the INCF German Node demonstrate for a range of parameter settings that the analysis scheme composed of FIM, PSF and PSR allows to reliably detect active assemblies in massively parallel spike trains.
In Frontiers in Computational Neuroscience, members of the INCF German Node present a unified view on pairwise covariances in recurrent networks in the irregular regime.
Frontiers in Human Neuroscience | The goal of the Brain and Art special issue is to bring together the key experimental and theoretical research linking state-of-the-art knowledge about the Brain with the phenomena of Art.
Brain imaging techniques have recently been able to reveal awareness and even allow rudimentary communication in some patients who have been diagnosed as being in the vegetative state. In this Perspective in Nature Reviews Neuroscience, researchers discuss these developments and consider their diagnostic, judicial and ethical implications.
Computational Models in Oncology: from Tumor Initiation to Progression to Treatment, edited by Katarzyna A. Rejniak and Heiko Enderling.
In Frontiers in Neuroscience, Neuromorphic Engineering, researchers propose a method based on the Siegert approximation for Integrate-and-Fire neurons to map an offline-trained DBN (Deep Belief Networks) onto an efficient event-driven spiking neural network suitable for hardware implementation.
In Frontiers in Neuroinformatics, researchers present MOBBED, is a lightweight, easy-to-use, extensible toolkit that allows users to incorporate a computational database into their normal MATLAB workflow.
In Science, researchers discuss how human cerebral organoids grown in the lab may quickly advance our understanding of brain development and disease.
In Neuroinformatics, members of the INCF US community present VolRoverN, a software package that produces accurate, efficient, and automated 3D surface reconstructions from stacked 2D contour tracings.
In Neuroinformatics, members of the INCF US Node discuss the current disconnect between different levels of connectomic efforts. They suggest that neuron types could be a suitable conceptual bridge between projectomics and synaptomics.
AAAS/Science´s special issue on communication in science includes free news and reviews on the lack of scrutiny at open-access journals, the rarity of published negative studies, and publishing sensitive data.
In Neuroinformatics, researchers present Brainography, a customizable network visualization tool that creates three-dimensional brain representations based on any choice of cortical or subcortical parcellation of a brain.
In Neuroinformatics, members of the INCF US community use the BODB integrated environment in order to bring together several different but complementary computational models, by functionally decomposing them into brain operating principles (BOPs) which each capture a limited subset of the model’s functionality.
The Grid Computing and Clusters Team at Barcelona Supercomputing Center is proud to announce a new release, the first official, of the programming environment COMPSs, a set of tools that helps developers to program and execute their applications efficiently on distributed computational infrastructures.
In Frontiers in Neuroinformatics, researchers present a novel CPU/GPU simulation environment for large-scale biological networks, the NeoCortical Simulator version 6 (NCS6), a free, open-source, parallelizable, and scalable simulator, designed to run on clusters of multiple machines, potentially with high performance computing devices in each of them.
In Frontiers in Computational Neuroscience, members of the INCF Japan Node decode the lapse of time from neuronal population signals recorded from the frontal cortex of monkeys performing a multiple-interval timing task.
Members of the INCF German Node discuss the compositional structure of hand movements by analyzing and modeling neural and behavioral data obtained from experiments where a monkey (Macaca fascicularis) performed scribbling movements induced by a search task.
In Neuroinformatics, researchers discuss feature reduction techniques used with machine learning in neuroimaging studies.
We are pleased to announce that the Neuroimaging Informatics Tools and Resources Clearinghouse (NITRC) has recently added their repository to the INCF Dataspace. All data stored on NITRC will now be accessible via the Dataspace in the NITRC zone. The INCF Dataspace provides a single point of access to data repositories worldwide.
In Brain Imaging Methods, members of the INCF US Node discuss instrumentation bias in the use and evaluation of scientific software and make recommendations for reproducible practices in the computational sciences.
In Neuroinformatics, researchers present a faceted-search based approach for visualization of anatomy by combining a three dimensional digital atlas with an anatomy ontology.
In Frontiers in Neuroinformatics, members of the INCF US Node describe NeuroLex.org, a wiki-based website and knowledge management system. Its goal is to bring neurobiological knowledge into a framework that allows neuroscientists to review the concepts of neuroscience.
Nature Reviews Neuroscience asks five prominent neuroscientists about the goals of several ambitious collaborative projects that have attracted large amounts of funding and media attention in the past year.
INCF is entering an exciting new phase of growth and engagement with major international brain initiatives, and is therefore announcing a reorganization at the secretariat to prepare for increased collaboration and coordination of the global neuroscience community.
The HBP has reserved a portion of its ramp-up phase funding for specific research tasks to be carried out by new beneficiaries who will join the consortium in 2014. These new beneficiaries will be selected from proposals submitted in response to this Competitive Call.
In Neuroinformatics, members of the INCF Polish Node present 3dBAR, a repository of digital representations of different brain atlases in CAF format which we recently proposed and a repository of 3D models of brain structures.
In PNAS, researchers discuss brain-computer interfaces (BCIs) and how real-time functional MRI can serve as a platform for exploring information processing and frontoparietal and insula network-based regulation of whole-brain task signal-to-noise ratio.
In Science, researchers propose a universal method for classifying neuronal subtypes, in order to increase our understanding of the human brain.
In Nature Neuroscience, researchers examine single neuron spiking activity in human subjects performing a virtual spatial navigation task and show the presence of grid-like firing activity.
In Neuroinformatics, researchers present a modular, high performance, open-source database system that incorporates popular neuroimaging database features with novel peer-to-peer sharing, and a simple installation.
In Frontiers in Brain Imaging Methods, members of the INCF US Node publish a multi-site study that compares resting state fMRI amplitude of low frequency fluctuations (ALFF) and fractional ALFF (fALFF) between patients with schizophrenia (SZ) and healthy controls (HC).
Nature publishes three papers that use the retina as a model for mapping neuronal circuits from the level of individual synaptic contacts to the long-range scale of dendritic interactions.
Scientists from IBM (NYSE: IBM) unveiled a breakthrough software ecosystem designed for programming silicon chips that have an architecture inspired by the function, low power, and compact volume of the brain. The technology could enable a new generation of intelligent sensor networks that mimic the brain’s abilities for perception, action, and cognition.
In Frontiers in Neuroinformatics, researchers present a novel Python-based toolbox called HDDM (hierarchical drift diffusion model), which allows fast and flexible estimation of the the drift-diffusion model and the related linear ballistic accumulator model.
By exploiting the full computational power of the Japanese supercomputer, K computer, researchers from the RIKEN HPCI Program for Computational Life Sciences, the Okinawa Institute of Technology Graduate University (OIST) in Japan and Forschungszentrum Jülich in Germany have carried out the largest general neuronal network simulation to date.
New insights into the neural processes that underlie cognition and behaviour have led to discussions about the relevance of these discoveries for the criminal justice system. Conversely, laws can influence neuroscience. Nature Reviews Neurosciencepresents a series of articles that explore the interaction between neuroscience and the law.
In Frontiers in Computational Neuroscience, researchers present a software framework designed to set up and simulate a wide range of studies targeting the encoding of space in rats.
Frontiers in Neuroanatomy launches a new Research Topic. The aim is to examine theoretical and experimental work directed at a detailed and comprehensive quantitative understanding of neuroanatomy.
F1000 invites bioinformatics tool developers to submit software and web tool papers free of charge to F1000Research to promote their system of updating and threading papers. Use the code SOFT13 to submit your paper free of charge before 2014.
An interview on Open Access to research journals with Dr. Francis S. Collins, Director of the National Institutes of Health, and Jack Andraka, the 16-year-old inventor of a breakthrough cancer diagnostic and winner of the 2012 Intel International Science and Engineering Fair.
The United States and Europe are both planning billion-dollar investments to understand how the brain works. But the technological challenges are vast.
In Neuroinformatics, David Kennedy, member of the INCF US Node discusses the use of ‘ Institutional Authorship’ in the authorship list of manuscripts that utilize the resources of some consortia and organizations.
In Frontiers in Cellular Neuroscience, members of the INCF italian Node use a simplified mathematical network model to contrast the properties of spatial representations self-organized through simulated Hebbian plasticity with those of charts pre-wired in the synaptic matrix, a control case closer to the ideal notion of continuous attractors.
In Frontiers in Teleneurology, Australian researchers present M-DIP, a new imaging software that automates the direct data tiling, conversion, pre-tiling of brain images from Medical Imaging NetCDF (MINC), Neuroimaging Informatics Technology Initiative (NIFTI) to RAW formats; speeds up querying of imaging measurement; and displays high-level of images with three dimensions in real world coordinates.
In Brain Research Bulletin, researchers discuss how Default Mode Network (DMN)-based research provided insights into the intrinsic functional architecture of human brain, as well as inter-individual differences in structural connectivity and neural activations.
In Frontiers in Neuroinformatics, members of the INCF US Node describe the OpenFMRI project, which aims to provide the neuroimaging community with a resource to support open sharing of task-based fMRI studies.
In Neuroinformatics, researchers present HERMES, a toolbox for the Matlab® environment (The Mathworks, Inc), which is designed to study functional and effective brain connectivity from neurophysiological data such as multivariate EEG and/or MEG records.
The History of Neuroscience in Autobiography is a seven-volume book series, edited by Larry R. Squire, that details the lives and discoveries of eminent senior neuroscientists. The Society for Neuroscience (SfN) has provided the complete series for download (as PDFs).
In Neuroinformatics, researchers present Py3DN, an open-source application to analyze and visualize 3D data, and to construct mathematical representations of neuronal topology, detailed visualization and the possibility to define non-standard morphometric analysis on the neuronal structures.
In what’s being called a landmark development for neuroscience, members of the INCF German Node have created a 3D digital reconstruction of a complete human brain that for the first time shows the organ’s complex anatomy at the cellular level.
Members of the INCF Finnish Node discuss in Frontiers in Brain Imaging Methods how to uncover the commonalities in the brain activity of the two subjects, and propose a method that searches for linear transformations that output maximally correlated signals between the two brains.
In PLOS One, scientists discuss schizophrenia as a network disease, and question whether it is possible to explain its disrupted topological abnormalities just by alteration of local activation patterns.
In Frontiers in Neuroinformatics, researchers present The Virtual Brain (TVB), a neuroinformatics platform for full brain network simulations using biologically realistic connectivity
In Neuroinformatics, members of the INCF US Node discuss the MCIC Collection, a Shared Repository of Multi-Modal, Multi-Site Brain Image Data from a Clinical Investigation of Schizophrenia.
To handle large amounts of data from detailed brain models, IBM, EPFL, and ETH Zürich are collaborating on a new hybrid memory strategy for supercomputers. This will help the Blue Brain Project and the Human Brain Project achieve their goals.
The INCF short course Introduction to Neuroinformatics provides an introduction to and overview of a wide range of topics within Neuroinformatics by leading experts in the field. The application deadline is 15 July 2013.
In Nature Methods, experts outline the different technologies needed to obtain anatomical and functional brain maps across species, and discuss the importance of assembling these maps and what will be needed beyond them, to understand the functioning of the brain.
In Neuroimage, members of the INCF US Node characterize and discuss the complex branching architecture of cerebral arteries across a representative sample of the human population from magnetic resonance angiography. This is important for diagnosing, analyzing, and predicting pathological state.
In Frontiers of Neuroinformatics, Martin Telefont (Blue Brain Project, École Polytechnique Fédérale de Lausanne, Switzerland) reviews the book " Principles of Data Integration" by authors AnHai Doan, Alon Halevy and Zachary Ives.
Members of the INCF German Node publish in Frontiers in Neuroinformatics, propose a new assembly detection method based on frequent item set mining (FIM).
In 2013, eight students have been accepted and will be working over the summer mentored by volunteers from the INCF international scientific community from Germany, United Kingdom, France, United States, Poland, Australia, Sweden and India.
A team of scientists, led by ecologist Lucas Joppa of Microsoft Research, has published a commentary piece in the journal Science, highlighting what they say is a growing problem in research efforts. They suggest that an overreliance on source code that has not been properly vetted is increasingly leading to incorrect research effort results.
As open science neuroinformatics databases the Brede Database and Brede Wiki seek to make distribution and federation of their content as easy and transparent as possible. The databases rely on simple formats and allow other online tools to reuse their content. This paper describes the possible interconnections on different levels between the Brede tools and other databases.
In Frontiers in Neuroinformatics, researchers present a Matlab package that makes it easy to apply population decoding analyses to neural activity. The design of the toolbox revolves around four abstract object classes which enables users to interchange particular modules in order to try different analyses while keeping the rest of the processing stream intact.
Frontiers announces the launch of a new journal, Frontiers in Bioengineering and Biotechnology. A broad scope journal covering all specialties, Frontiers in Bioengineering and Biotechnology will provide a single open-access platform for diverse and emerging bioengineering and biotechnology research to be disseminated and discussed.
In Nature, researchers define the various functions of sleep, from how we learn to the regulation of metabolism and immunity. New ways to treat troubled sleeping are being developed, and better sleep practice can help people with mood disorders.
In Frontiers of Neuroinformatics, members of the INCF US Node, explore the use of ontologies to create formal descriptions of structural phenotypes across scales that are machine processable and amenable to logical inference.
In Frontiers of Computational Neuroscience, researchers suggest a new biophysical motivated derivation of a single compartment model that integrates the non-linear effects of shunting inhibition, where an inhibitory input on the route of an excitatory input to the soma cancels or “shunts” the excitatory potential.
In Frontiers of Computational Neuroscience, researchers discuss how a better understanding of astrocyte-neuron coupling may lead to providing building blocks for studying the regulatory capability of astrocytic networks on a larger scale, through nine papers which cover a range of issues from computational models of astrocyte-neuron interactions to the role of astrocytes in neurological disorders.
To facilitate the quantification of neuronal cell patterns, researchers have developed RipleyGUI, a MATLAB-based software that can be used to detect patterns in the 3D distribution of cells.
In Science, researchers report a link between cognitive challenges, adult brain neurogenesis, and the development of individuality. This relationship supports the idea that a key function of adult neurogenesis is to shape neuronal connectivity in the brain according to individual needs.
In Nature, researchers discuss how inflammation-activated signalling pathways in the brain's hypothalamus control the production of ageing-related hormones. This finding provides a link between inflammation, stress responses and systemic ageing.
To celebrate the European Month of the Brain, researchers funded by the European Research Council (ERC) will participate in two key events organised by the European Commission in Brussels on 14 May, and in Dublin on 27 and 28 of May 2013. On this occasion, the ERC has issued a new publication entitled 'ERC projects to unlock mysteries of the human brain'.
In PNAS, researchers describe a strategy designed to identify RNAs that are actively transported to synapses during learning. Their approach is based on the characterization of RNA transport complexes carried by molecular motor kinesin.
This Newsletter features: Launch of Victoria Node, INCF Short courses for 2013, HBP wins top European science funding, Profiles in Neuroinformatics: A new INCF blog feature and Publications in Brief.
From next month, Nature and the Nature research journals will introduce editorial measures to address the problem of irreproducibility by improving the consistency and quality of reporting in life-sciences articles.
For the third year, INCF will participate as a mentoring organization in the Google Summer of Code program with more than ten project proposals. Student application ends on May 3rd. Apply today!
In PNAS, researchers discuss how by viral expression of neural fate determinants, it is possible to directly reprogram mouse and human fibroblasts into functional neurons, also known as induced neurons. The resulting cells can be used for obtaining patient- and disease-specific neurons to be used for disease modeling and for development of cell therapy.
In early April EUDAT was glad to welcome a new Associated Partner: the International Neuroinformatics Coordinating Facility (INCF). The INCF's involvement in the development of EUDAT services will focus mainly on testing and using the services that are relevant for the Neuroinformatics community.
In Nature Neuroscience Reviews, researchers discuss the inter-individual differences in the thickness or volume of a brain region, which often co-vary with inter-individual differences in other brain regions. They discuss this phenomenon of structural co-variance, its underlying mechanisms and its potential value in the understanding of various brain disorders.
In Nature Neuroscience Reviews, researchers review our current understanding of the role of astrocytes (formation, maturation, function and elimination of synapses and support the formation of appropriate neural circuits) and highlight unanswered questions for future research.
Researchers discuss in Nature how hippocampal place cells encode information about an animal’s spatial world and how these same neurons envisage a future journey moments before a rat sets off.
Researchers discuss the birth and development of the field of Neuroinformatics in this paper published at the Official Journal of the American Academy of Neurology, and acknowledge the coordinative role of INCF.
The twelfth annual Wiley Prize in Biomedical Sciences has been awarded to Dr. Michael Young, Dr. Jeffrey Hall, and Dr. Michael Rosbash for the discovery of the molecular mechanisms governing circadian rhythms.
In Nature, scientists at Stanford University have made a whole mouse brain, and part of a human brain, transparent so that networks of neurons that receive and send information can be highlighted in stunning color and viewed in all their three-dimensional complexity without slicing up the organ, and preserve the biochemistry of the brain as well.
Researchers at the University of Calgary's Hotchkiss Brain Institute have discovered that stress circuits in the brain undergo profound learning early in life. Using a number of cutting edge approaches, including optogenetics, Jaideep Bains, PhD, and colleagues have shown stress circuits are capable of self-tuning following a single stress. These findings demonstrate that the brain uses stress experience during early life to prepare and optimize for subsequent challenges.
Nature Publishing Group NPG announces the Spring 2014 launch of Scientific Data. Open for submissions this autumn, Scientific Data is a new open-access, online-only platform for the publication of descriptions of scientifically valuable datasets. Scientific Data will initially focus on experimental datasets from the life, biomedical and environmental science communities with future plans to expand to other fields in the natural sciences.
This year's "Brain Prize" by the Grete Lundbeck European Brain Research Prize Foundation will be awarded to six leading scientists for their joint development of "optogenetics". Bernstein network member Ernst Bamberg (BFNT Göttingen and Max Planck Institute of Biophysics, Frankfurt), Peter Hegemann, Georg Nagel (both Germany), Gero Miesenböck (Austria), Ed Boyden and Karl Deisseroth (both USA) are this year's awardees.
In Frontiers of Neural Circuits, using computational tools, researchers explore the impact of local synaptic inhibition on the plasticity of excitatory synapses in dendrites and characterized the dependence of excitatory synaptic plasticity on dendritic morphology, loci and strength, as well as on the spatial distribution of inhibitory synapses and on the level of excitatory activity.
President Obama unveiled the “BRAIN” Initiative—a bold new research effort to revolutionize our understanding of the human mind and uncover new ways to treat, prevent, and cure brain disorders like Alzheimer’s, schizophrenia, autism, epilepsy, and traumatic brain injury. The BRAIN Initiative calls for historic investments in research and development to fuel the innovation, job creation, and economic growth that together create a thriving middle class.
In Frontiers of Neuroanatomy, members of the US Node hypothesize and detail 7 functional circuits corresponding to psychological perspectives on the brain: consolidated long-term declarative memory, short-term declarative memory, working memory/information processing, behavioral memory selection, behavioral memory output, cognitive control, and cortical information flow regulation.
In Frontiers of Neural Circuits, members of the INCF Japan and Germany Node discuss how in motor cortex, a precise spatio-temporal pattern of activation is involved for the control of reach-to-grasp movements and provide some new insight about the functional organization of motor cortex during reaching and object manipulation.
The primary goal of this proposal is to highlight and detail ITKv4’s segmentation and registration methodology and its application to a variety of neuroinformatics problems. By using ITKv4 as a core platform and disseminating the analysis pipelines, the papers selected by this proposal will promote reproducible practices and act as a guide for other researchers who wish to use ITKv4 in their own research.
INCF Short Courses for 2013 are: Introduction to Neuroinformatics (Stockholm, Sweden), Imaging the brain at different scales: How to integrate multi-scale structural information? (Antwerp, Belgium), Neuroinformatics, Neurogenomics and Brain Disease (Fraueninsel -Bavaria-, Germany), and
Achieving Excellence in Neuroinformatics in Latin America (Havana, Cuba).
The Brain Prize - Denmark's 1 million euro brain research prize - is awarded to six leading scientists for the development of ‘optogenetics’, a revolutionary technique that advances our understanding of the brain and its disorders.
The mechanisms of perception, cognition, and action remain mysterious because they emerge from the real-time interactions of large sets of neurons in densely interconnected, widespread neural circuits. In Science, researchers propose building technologies to enable comprehensive mapping of neural circuit activity to understand brain function and disease.
In PNAS, researchers Investigate the distribution of spatial patterns, since recent functional magnetic resonance imaging studies have shown that the brain is remarkably active even in the absence of overt behavior, and this activity occurs in spatial patterns that are reproducible across subjects and follow the brain’s established functional subdivision.
In PNAS, researchers discuss how neurons in mammals do not undergo replicative aging, and, in absence of pathologic conditions, their lifespan is limited only by the maximum lifespan of the organism.
Brain Awareness Week (BAW) is the global campaign to increase public awareness of the progress and benefits of brain research.Every March, BAW unites the efforts of partner organizations worldwide in a celebration of the brain for people of all ages. Events are limited only by the organizers’ imaginations and include open days at neuroscience labs; exhibitions about the brain; lectures on brain-related topics; displays at libraries and community centers; classroom workshops; and more.
Launched the research topic Python in Neuroscience II in Frontiers in Brain Imaging Methods. Article submissions now open! Deadline for full article submission: 15 Jul 2013 Extended deadline for full article submission: 15 Aug 2013
Members of the Bernstein Center have developed a neuroinformatics platform with a brain simulator that incorporates a range of neuronal models and dynamics at its core. This integrated framework allows the model-based simulation, analysis and inference of neurophysiological mechanisms over several brain scales that underlie the generation of macroscopic neuroimaging signals.
A study published in Nature Neuroscience finds that microglia are quite distinct from blood-borne macrophages and derive from an erythromyeloid precursor cell of the embryonic hematopoiesis.
Frontiers is joining forces with Nature Publishing Group (NPG) in a strategic alliance to support and develop open access publishing.
Frontiers in Neuroinformatics special topic “Recent advances and the future generation of neuroinformatics infrastructure” call for papers. Deadline for Abstract Submission: 31 Jul 2013. Deadline for Article Submission: 31 Oct 2013.
In Nature Reviews Neuroscience, researchers discuss the neural mechanisms underlying the perception of duration and present recent theoretical developments and empirical findings indicating that 'climbing' neural activity has a central role in time perception.
In Nature Reviews Neuroscience, INCF members describe a possible taxonomical solution for classifying GABAergic interneurons of the cerebral cortex based on a novel, web-based interactive system that allows experts to classify neurons with pre-determined criteria.
In Frontiers of Computational Neuroscience, researchers describe a model for cortical development, synchrony and synaptic self-organization, that solves long-standing difficulties of earlier models.
In Frontiers of Neuroinformatics, researchers describe the NEuronMOrphological analysis tool NEMO. Morphometric analysis of neurons and brain tissue is relevant to the study of neuron circuitry development during the first phases of brain growth or for probing the link between microstructural morphology and degenerative diseases.
In Nature, researchers discuss the complexity of bilingual acquisition in bilingual infants, how perceptually available cues like prosody can bootstrap grammatical structure and how and why infants acquire grammar so early and effortlessly.
In Frontiers in Systems Neuroscience, members of the INCF Japan and German Node discuss the cross-frequency interaction of the eye-movement related local field potential (LFP) signals in V1 of freely viewing monkeys.
Professor, researcher, neuroscientist and author, David Willshaw talks to INCF about his research, projects and achievements.
In PLoS One, INCF researchers replicate normal and pathological patterns of visual scanning, line bisection, and the differences between hemianopia and hemineglect. This model will help explain why compensatory processes that counter the effects of hemianopia are ineffective in hemineglect.
In Frontiers in Neurology Education, Lawrence Korngut, from the Department of Clinical Neurosciences, Hotchkiss Brain Institute (Canada), reviews the application Pocket Brain for iPhone and iPad.
In Frontiers of Neuroinformatics, US researchers discuss the extent to which homotypic forces might influence real dendritic morphologies, and speculate about the influence of other environmental cues on neuronal shape and circuitry.
Nature Neuroscience dedicates its latest issue to memory, comprising Commentaries, Reviews and Perspectives discussing some of the most exciting recent developments and emerging ideas in our understanding of the neurobiology of learning and memory.
In Frontiers of Computational Neuroscience, researchers discuss how protein amyloid-beta concentration perturbs pre-synaptic release in hippocampal neurons through a computational model. The results suggest that the increased protein significantly contribute to abnormal hippocampal function during Alzheimer´s Disease.
The Human Brain Project (HBP), a Swiss based effort that comprises 87 organisations in 23 different countries (of which 16 are European) including universities, research organisations and industry, has been awarded one of European Commission FET Flagship projects. The new project will federate European efforts to address one of the greatest challenges of modern science: understanding the human brain.
In Nature Neuroscience Reviews, researchers discuss several animal models for Traumatic Brain Injury (TBI), to better understand the underlying pathophysiology and to explore potential treatments.
Dr Upinder Bhalla, member of the INCF India Node, National Centre for Biological Sciences Bangalore, India, talks to INCF about his life as neuroinformatics researcher, projects and interests.
In Nature, Chris A. Mattmann explains "to get the best out of big data, funding agencies should develop shared tools for optimizing discovery and train a new breed of researchers"
Frontiers of Neuromorphic Engineering has accepted a paper by members of the INCF German Node, in which they present a highly configurable neuromorphic computing substrate and use it for emulating several types of neural networks and describe the successful emulation of six different neural networks which cover a broad spectrum of both structure and functionality.
In Trends of Cognitive Sciences, researchers discuss how the scientific community often maintains an overly simplistic linear view without considering the perspective of the neurons. In order to understand the brain, only the neurons’ perspective matters, thus change in the neuroscientists’ perspective is needed.
In Neuroinformatics, US researchers present a a graphics processing unit accelerated motion correction algorithm and modular system for real-time fMRI, a motion correction algorithm that provides an estimate of motion with essentially no processing delay as well as a modular rt-fMRI system design.
Under the direction of Abigail Morrison, neuroscientists, physicians, computer scientists, mathematicians and physicists can work intensively together in order to optimize the use of computer simulations of the brain for supercomputers.
In Nature Neuroscience, researchers explain how using simultaneous quadruple-octuple in vitro and dual in vivo whole-cell recordings, they found two previously unknown interneuronal circuits that link cortical layer 1–3 (L1–3) interneurons and L5 pyramidal neurons in the rat neocortex.
In Frontiers of Computational Neuroscience, members of the INCF Germany Node discuss how movement representation facilitates learning significantly and leads to better generalization to new task settings without re-learning.
Are you producing valuable data? Are you producing reusable data? INCF and One Mind for Research have launched the Data Share Award, offering $10,000 in prize money and hosting, to encourage individuals, research groups, and organizations to make their datasets open and freely accessible to all through the INCF Dataspace.
Members of the INCF UK Node have recently published in Frontiers of Psychiatry Higher how late-life depression is associated with overall increased functional connectivity strength and changes in the average distance between connected nodes.
F1000Research is a far-reaching alternative Open Access publishing program in biology and medicine, that challenges traditional scholarly publishing models by defining new standards for its speed, peer review, data publication and for publishing good science.
In Frontiers of Neuroinformatics, members of the INCF Germany Node develop a scalable, low-cost and open source solution for continuous integration (CI), a technique that ensures the quality of changes to the code base during the development procedure, rather than relying on a pre-release integration phase.
In Frontiers of Neuroinformatics, members of the INCF Germany and Netherlands Nodes discuss the features of the CoCoMac 2.0 database, which contains the results of several hundred published axonal tract-tracing studies in the macaque monkey brain, and how they compare to six connectome related projects.