People

Research focus: My particular interests are: Synaptic plasticity, noise in neural systems, cortical dynamics in vision

Research focus: My research focuses on neural mechanisms underlying perceptual decision making and learning in the primate brain by combining modelling, behavioural measurements and functional MRI techniques. Recently, I investigate how human may learn novel visual patterns that do not appear in their daily lives. I am also interested in neuroimaging data analysis by machine learning methods.

Research focus: Develop services and infrastructure for spatial integration of brain data

INCF activities: Digital Brain Atlasing | Digital Atlasing Infrastructure Task Force Lead

Research focus: Our laboratory is interested in how the basal forebrain is organized to modulate sensory and higher order cognitive functions in the cerebral cortex.

INCF activities: Ontologies of Neural Structures | Structural Lexicon Task Force

Research focus: .

Research focus: We are studying information processing in thalamo-cortico-thalamic loops in mammal sensory systems concentrating on the visual system of the cat and the somatosensory system of the rat. In particular we are interested in mechanisms of context-dependent modulation of information processing.   To achieve our goals we develop new methods of data analysis, test it on different models of the studied systems, and analyze the experimental data. We concentrate on analysis and modeling of electrophysiological data, both spike trains and local field potentials.

Research focus: Current research in the laboratory focuses on understanding dynamic operations within sensory systems of behaving animals. Using electrophysiological recording techniques and neuroinformatic methods for data analysis we are trying to correlate the activation of specific neuronal networks with its behavioral context. Five parallel projects are under investigation:   Current research activities    *   electrophysiological correlates of visual attention in cats - temporal analysis (frequency, phase and amplitude's envelope) of local field potentials registered from different parts of cat's thalamo-cortical system during behavioral task based on intermingled trials of delayed spatial discrimination of visual or auditory stimuli;  *   information processing in the cortico-thalamic part of the rat's somatosensory system - the role of primary and secondary sensory pathways in different behavioral situations; in vitro electrophysiological investigations of synaptic properties and cellular connections within the cortico-thalamic loop of rodent's somatosensory system;  *   the role of extrageniculate visual pathway in movement perception - electrophysiological and modeling investigations on the spatial and temporal properties of single units' receptive fields in the cat; coding of information in geniculate and extrageniculate visual pathways in the cat - electrophysiological and computational studies on temporal pattern of neuronal activity;  *   application of nonlinear and wavelet methods for time series analysis; theoretical studies of models of cortico-thalamic loops in visual and somatosensory systems; white-noise and information theoretical analysis of spike trains; development of new current source density techniques for the analysis of three dimensional data.  

Research focus: The application of the methods of computational neurobiology -- mathematical analysis and computer simulation -- to an understanding of the development and functioning of the nervous system. Specific areas of interest: 1. The mechanisms by which retinotopically ordered projections and patterns of ocular dominance are developed between vertebrate eye and brain. 2. The mechanisms for the elimination of polyinnervation in developing muscle. 3. The functioning of the basal ganglia and related structures and their role in Parkinson's Disease. 4. The role of the mammalian hippocampus, cerebellum and neocortex in the associative storage and retrieval of information in the brain. 5. The development of neurally inspired algorithms for hard computational problems, such as combinatorial optimisation

Research focus: I am interested in integrated and integrative software infrastructure supporting life-science research activities in the fields of neuroscience, genomics and genetics.

Research focus: Activity of Dopaminergic and Glutametergic stimuli at the striatum