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Full nameSharon Crook |
AffiliationCenter for Adaptive Neural Systems |
AddressSchool of Math. & Stat. Sciences 1804
Arizona State University
85287-1804
Tempe
United States
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sharon.crook(at)asu.edu
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Home pagehttp://math.asu.edu/~crook |
PhoneOffice: 480 965 0403 |
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Research Areas
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KeywordsNeuroML, Model Reproducibility, Multiscale Modeling, Structural Plasticity |
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Research focusOne of the major challenges in neuroscience is to understand the biophysical mechanisms and algorithms underlying neural computation. In my laboratory, we use mathematical models, analysis, and computer simulations to examine the dynamics of neurons and neuronal networks and to understand the mechanisms underlying plasticity in neuron or network behavior due to trauma, rehabilitation, learning or development. Our current research focuses on several related topics including 1) how alterations in dendritic morphology, synapse distributions and membrane properties affect cell dynamics and 2) the roles of synaptic activity, intracellular calcium, and neuromodulators in plasticity and development. My research group also contributes to an international effort to create standards for describing models in neuroscience. NeuroML provides a common description language for neuroanatomical data, for the biophysical properties of membranes, and for network connectivity for use in model specifications. These standards can be used by down-stream software applications to aid model exchange and simulator interoperability. |
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QuoteAs neuroscience models become more complex and extend to multiple scales, efforts to promote model reproducibility in our community will have profound effects on the quality and reliability of computational approaches. |
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| Profile updated: 2012-04-16 | |||
