Over the last decade interest in diffusion MRI has exploded. The technique provides a unique insight into the microstructure of living tissue and enables in-vivo connectivity mapping of the brain. Microstructural changes are often the earliest signs of disease or tissue regeneration, as well as being manifestation of physiological processes in normal tissue functioning. Tractography and connectivity mapping give fundamental new insights in neuroscience and neuroanatomy. The variety of clinical applications is expanding rapidly and includes detection of lesions and damaged tissue, prognosis of functional impairment and neurosurgical planning.

Computational techniques are key to the continued success and development of diffusion MRI and to its widespread transfer into the clinic. New processing methods are essential for addressing issues at each stage of the diffusion MRI pipeline: acquisition, reconstruction, modeling and model fitting, image processing, fiber tracking, connectivity mapping, visualization, group studies and inference. The workshop will give a snapshot of the current state of the art.